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Additionally, oral supplements can cause mild stomach discomfort or prove less effective due to inadequate intestinal absorption

An associative induction protocol (burst frequency stimulation of mossy fibers paired with postsynaptic spikes) induced LTP in these cells while a nonassociative protocol (same burst frequency stimulation but paired with hyperpolarization preventing spikes) induced LTD (Alle et al., 2001

Mol Neurobiol 111 Gellera C, Meoni C, Castellotti B, Zappacosta B, Girotti F, Taroni F et al (1996) Errors in Huntington disease diagnostic test caused by trinucleotide deletion in the IT15 gene

doi: 10.1186/s13075-021-02580-1 25 MartinonFPtrilliVMayorATardivelATschoppJ

The zebrafish modelcharacterized by high-throughput screening capacity, optical transparency, genetic tractability, and cost efficiencyis rapidly transitioning from a basic research tool to a pivotal platform bridging mechanistic investigation and clinical translation (Figure 5A) (Patton et al., 2021