This article is a systematic review of the effect of psychosocial factors on IC/BPS, of the comorbid anxiety, depression and QOL issues that might increase IC/BPS symptoms, and of the self-management interventions that might be helpful
Green tea EGCG inhibits DNMTs leading to hypomethylation of the tumour suppressor gene promoters (e.g., p16, RAR) and re-expression of pro-apoptotic genes as well as it interferes with RTK signalling NF-B activation that are associated with inflammatory and proliferative signals (16)
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